Position: Home > Members > Senior > Ping Ao

 

 Ping Ao (敖平)

 Chang Jiang Distinguished Professor 

 Address : Key Laboratory of Systems

  Biomedicine, Ministry of Education,

  Shanghai Center for Systems Biomedicine,

  Shanghai, 200240, China

 Office : Room C203,

  Systems Biomedicine Building

  Email : aoping AT sjtu.edu.cn

 

Education

  • 1983, B.S. in physics, Peking University, Beijing, PR China;
  • 1985, M.A. in physics, University of Illinois at Urbana-Champaign, USA;
  • 1990, Ph.D. in physics, University of Illinois at Urbana-Champaign, USA; PhD supervisor: A.J. Leggett;
  • 1994, Postdoc. in physics, University of Washington, Seattle, USA; Supervisor: D.J. Thouless.

Employment History

  • 1994-2000 Department of Theoretical Physics, Umeå University, Umeå, SWEDEN;
  • 2000-2003 Senior Research Scientist, Institute for Systems Biology, Seattle, USA;
  • 2003 Visiting Associate Professor, Professor, Keck Graduate Institute, Claremont, USA;
  • 2003-2009 Research Associate Professor, Department of Mechanical Engineering, University of Washington, Seattle, USA;
  • 2008-Present Professor, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.

Research

Prof. Ping Ao's research is interdisciplinary, ranging from biology, to engineering, to physics. Both dry and wet approaches have been employed.

  • In (systems) biology, his research consists of four major programs: cancer network dynamics, metabolism, evolutionary biology, and stochastic dynamics.
  • In physics, research on condensed matter physics and non-equilibrium physics is still active.

Recently, his group has been developing a new method on stochastic differential equations, and have solved two fundamental problems in evolutionary biology; found the first generic construction of Lyapunov function in whole state space; and formulated a cancer dynamical and a kinetic metabolic pathway frameworks.

Publications

Selected Journal Papers:

  • Yuan, R.-S.; Wang, X.-A.; Ma, Y.-A.; Yuan, B. & Ao, P., Exploring a Noisy van der Pol Type Oscillator with a Stochastic Approach, Physical Review E, 2013, 87, 062109
  • Ao, P.; Chen, T.-Q. & Shi, J.-H., Dynamical Decomposition of Markov Processes without Detailed Balance, Chinese Physics Letters, 2013, 30 (7) ,070201
  • Tang, K.-C.; Ao, P. & Yuan, B., Robust Reconstruction of the Fokker-Planck Equations from Time Series at Different Sampling Rates, Europhysics Letters, 2013, 102 (4), 40003
  • Wang, G.-W.; Zhu, X.-M.; Hood, L. & Ao, P., From Phage Lambda to Human Cancer: Endogenous Molecular-Cellular Network Hypothesis, Quantitative Biology, 2013
  • Yuan, R.-S. & Ao, P., Beyond Itô versus Stratonovich, Journal of Statistical Mechanics: Theory and Experiment2012, P07010
  • Shi, J.-H.; Chen, T.-Q.; Yuan, R.-S.; Yuan, B. & Ao, P., Relation of a New Interpretation of Stochastic Differential Equations to Ito Process, Journal of Statistical Physics2012, 148 (3), 579-590
  • Friston, K. & Ao, P., Free-energy, Value and Attractors, Computational and Mathematical Methods in Medicine, 2012, 2012, 937860
  • Jiao, S.-Y. & Ao, P., Absorbing Phenomena and Escaping Time of Muller's Ratchet in Adaptive Landscape, BMC Systems Biology2012, 6 (Suppl 1), S10
  • Xu, M.-J.; Liu, X.-J.; Zhao, Y.-L.; Liu, D.; Xu, Z.-H.; Lang, X.-M.; Ao, P.; Lin, W.-H.; Yang, S.-L.; Zhang, Z.-G. & Xu, J., Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis, Marine Drugs, 2012, 10 (3), 639 - 654
  • Kwon, C. & Ao, P., Nonequilibrium Steady State of a Stochastic System Driven by a Nonlinear Drift Force, Physical Review E, 2011, 84, 061106
  • Xu, W.; Yuan, B. & Ao, P., Construction of Lyapunov Function for Dissipative Gyroscopic System, Chinese Physics Letters2011, 28, 050201
  • Xu, M.-J.; Zhu, X.-M.; Lin, B.-H. & Ao, P., Generic Enzymatic Rate Equation, Progress in Biochemistry and Biophysics, 2011, 38 (8), 759 - 767
  • Ao, P.; Galas, D.; Hood, L.; Yin, L. & Zhu, X. M., Towards Predictive Stochastic Dynamical Modeling of Cancer Genesis and Progression, Interdisciplinary Sciences: Computational Life Sciences, 2010, 2, 140-144
  • Ao, P., Global View of Bionetwork Dynamics: Adaptive Landscape, Journal of Genetics and Genomics, 2009, 36, 63 - 73
  • Ao, P.; Lee, L. W.; Lidstrom, M. E.; Yin, L. & Zhu, X.-M., Towards Kinetic Modeling of Global Metabolic Networks with Incomplete Experimental Input on Kinetic Parameters, Chinese Journal of Biotechnology, 2008, 24, 980-994
  • Ao, P.; Galas, D.; Hood, L. & Zhu, X., Cancer as Robust Intrinsic State of Endogenous Molecular-Cellular Network Shaped by Evolution, Medical Hypotheses2008, 70, 678-684
  • Ao, P., Emerging of Stochastic Dynamical Equalities and Steady State Thermodynamics from Darwinian Dynamics, Communications in Theoretical Physics, 2008, 49, 1073
  • Ao, P., Borges Dilemma, Fundamental Laws, and Systems Biology, Bioinformatics and Biology Insights, 2008, 2, 201 - 202
  • Ao, P.; Kwon, C. & Qian, H., On the Existence of Potential Landscape in the Evolution of Complex Systems, Complexity, 2007, 12, 19 - 27
  • Ao, P., Darwinian Dynamics Implies Developmental Ascendency, Biological Theory, 2007, 2 (2007), 113 - 115
  • Lee, L.; Yin, L.; Zhu, X. & Ao, P., Generic Enzymatic Rate Equation under Living Conditions, Journal of Biological Systems, 2007, 15, 495 - 514
  • Olson, J. C. & Ao, P., Nonequilibrium Approach to Bloch-Peierls-Berry Dynamics, Physical Review B, 2007, 75 (3), 035114
  • Yin, L. & Ao, P., Existence and Construction of Dynamical Potential in Nonequilibrium Processes without Detailed balance, Journal of Physics A: Mathematical and General, 2006, 39, 8593
  • Ao, P., Metabolic Network Modelling: Including Stochastic Effects, Computers & Chemical Engineering, 2005, 29, 2297 - 2303
  • Ao, P., Laws in Darwinian Evolutionary Theory, Physics of Life Reviews, 2005, 2, 117 - 156
  • Kwon, C.; Ao, P. & Thouless, D. J., Structure of Stochastic Dynamics near Fixed Points, Proceedings of the National Academy of Sciences USA, 2005, 102, 13029 - 13033
  • Han, J. H.; Kim, J. S.; Kim, M. J. & Ao, P., Effective Vortex Mass from Microscopic Theory, Physical Review B, 200571 (12), 125108
  • Yin, L. & Ao, P., Phase Slip in a Superfluid Fermi Gas near a Feshbach Resonance, Physical Review A, 2005, 71 (4), 041603(R)
  • Zhu., X.-M.; Yin, L.; Hood, L. & Ao, P., Calculating Biological Behaviors of Epigenetic States in the Phage λ Life Cycle, Functional & integrative genomics, 2004, 4 (3), 188 - 195
  • Ao, P., Potential in Stochastic Differential Equations: Novel Construction, Journal of Physics A: Mathematical and General, 2004, 37, L25 - L30
  • Emmanouilidou, A.; Zhao, X.-G.; Ao, P. & Niu, Q., Steering an Eigenstate to Destination, Physical Review Letters, 2000, 85 (8), 1626 - 1629
  • Lundh, E. & Ao, P., Hydrodynamic Approach to Vortex Lifetimes in Trapped Bose Condensates, Physical Review A, 2000, 61 (6), 063612
  • Ao, P., Origin of Hall Anomaly in the Mixed State, Physical Review Letters, 1999, 82 (11), 2413
  • Ao, P. & Chui, S. T., Binary Bose-Einstein Condensate Mixtures in Weakly and Strongly Segregated Phases, Physical Review A, 199858 (6), 4836 - 4848
  • Wexler, C.; Thouless, D. J.; Ao, P. & Niu, Q., Berry's Phase and the Magnus Force for a Vortex Line in a Superconductor etc, Physical Review Letters1998, 81 (19), 4277
  • Ao, P., Invalidity of Classes of Approximated Hall Effect Calculations, Physical Review Letters, 1998, 80 (22), 5025
  • Wexler, C.; Thouless D. J.; Ao, P. & Niu, Q., Magnus and Iordanskii Forces in Superfluids, Physical Review Letters, 1998, 80 (19), 4357
  • Zhu, X.-M.; Tan, Y. & Ao, P., Effects of Geometric Phases in Josephson Junction Arrays, Physical Review Letters, 1996, 77 (3), 562 - 565
  • Thouless, D. J.; Ao, P. & Qian, N., Transverse Force on a Quantized Vortex in a Superfluid, Physical Review Letters, 1996, 76 (20), 3758 - 3761
  • Qian, N.; Ao, P. & Thouless, D. J., From Feynman's Wave Function to the Effective Theory of Vortex Dynamics, Physical Review Letters, 1995, 75 (5), 975
  • Ao, P. & Zhu, X.-M., Quantum Interference of a Single Vortex in a Mesoscopic Superconductor, Physical Review Letters, 1995, 74 (23), 4718 - 4721
  • Aitchison, I. J. R.; Ao, P.; Thouless, D. J. & Zhu, X.-M., Effective Lagrangians for BCS Superconductors at T=0, Physical Review B, 199551 (10), 6531 - 6535
  • Ao, P., Magnetic Field Effect on an Electron Tunneling out of a Confining Plane, Physical Review Letters, 1994, 72 (12), 1898 - 1901
  • Qian, N., Ao, P. & Thouless, D. J., From Feynman's Wave Function to the Effective Theory of Vortex Dynamics, Physical Review Letters, 1994, 72 (2), 1706 - 1709
  • Ao, P. & Thouless, D. J., Tunneling of a Quantized Vortex: Roles of Pinning and Dissipation, Physical Review Letters, 1994, 72 (1), 132 - 135
  • Ao, P. & Thouless, D. J., Berry's Phase and the Magnus Force for a Vortex Line in a Superconductor, Physical Review Letters, 1993, 70 (14), 2158 - 2161
  • Ao, P., Single Vortex Tunneling in a Superconducting Film, Physical Review Letters, 1992, 69 (20), 2997 - 3000
  • Ao, P., Quantum Dynamics of a Two-state System in a Dissipative Environment, Physical Review B, 199143 (7), 5397 - 5418
  • Goldbart, P. & Ao, P., Intrinsic Torsional Viscosity of Nematic Liquid Crystal, Physical Review Letters, 1990, 64 (8), 910 - 913
  • Ao, P. & Rammer, J., Influence of dissipation on the Landau-Zener transition, Physical Review Letters, 198962 (25), 3004 - 3007
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